Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL840739 | 1.00 | KMT2A (0.43) | KMT2AMAPTMEN1SMN1; SMN2LMNA | |
| SCHEMBL838833 | 0.83 | KMT2A (0.51) | KMT2AMAPTMEN1SMN1; SMN2LMNA | |
| SCHEMBL838834 | 0.83 | KMT2A (0.51) | KMT2AMAPTMEN1SMN1; SMN2LMNA | |
| SCHEMBL4476068 | 0.81 | KMT2A (0.51) | KMT2AMAPTMEN1SMN1; SMN2LMNA | |
| SCHEMBL4476063 | 0.81 | KMT2A (0.51) | KMT2AMAPTMEN1SMN1; SMN2LMNA | |
| SCHEMBL839053 | 0.76 | KMT2A (0.44) | KMT2AMAPTMEN1SMN1; SMN2LMNA | |
| SCHEMBL839052 | 0.76 | KMT2A (0.44) | KMT2AMAPTMEN1SMN1; SMN2LMNA | |
| SCHEMBL7604606 | 0.76 | PTPN1 (0.43) | KMT2AMEN1SMN1; SMN2LMNAHTT | |
| SCHEMBL840738 | 0.75 | ALDH1A1 (0.46) | KMT2AMAPTMEN1SMN1; SMN2LMNA | |
| SCHEMBL28775044 | 0.75 | ALDH1A1 (0.46) | KMT2AMAPTMEN1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143052-B2 | Process for preparing optically active (S or R)-α amino acid and (R or S)-α amino acid ester in one phase organic reaction medium | UBE INDUSTRIES, LTD. (JP) | 2012-03-27 | — | — | US | disclosed |