Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.65 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.64 |
| ▸ | CTSL | P07711 | 6/20 | 0.61 |
| ▸ | CTSB | P07858 | 4/20 | 0.61 |
| ▸ | CTSS | P25774 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164724 | 0.91 | CTSK (0.67) | CTSKCAPN1CTSLCTSBCTSS | |
| SCHEMBL3165013 | 0.89 | CTSK (0.67) | CTSKCAPN1CTSLCTSBCTSS | |
| SCHEMBL27509912 | 0.86 | CTSK (0.70) | CTSKCAPN1CTSLCTSBCTSS | |
| SCHEMBL27509913 | 0.86 | CTSK (0.70) | CTSKCAPN1CTSLCTSBCTSS | |
| SCHEMBL7165055 | 0.86 | CTSK (0.66) | CTSKCAPN1CTSLCTSBCTSS | |
| SCHEMBL6825534 | 0.86 | CAPN1 (0.74) | CTSKCAPN1CTSLCTSBCTSS | |
| SCHEMBL5848800 | 0.84 | CTSK (0.70) | CTSKCAPN1CTSLCTSBCTSS | |
| SCHEMBL5848511 | 0.84 | CTSK (0.70) | CTSKCAPN1CTSLCTSBCTSS | |
| SCHEMBL8823900 | 0.84 | CTSK (0.70) | CTSKCAPN1CTSLCTSBCTSS | |
| SCHEMBL20760624 | 0.84 | CTSK (0.77) | CTSKCAPN1CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998470-A | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1999-12-07 | — | — | US | disclosed |