SCHEMBL8407484

SCHEMBL8407484

CCCc1cc(CC(=O)NC)cc(C(C)(C)C)c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.51
GAA P10253 7/20 0.49
KMT2A Q03164 4/20 0.49
HIF1A Q16665 3/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 4/20 0.37
TSHR P16473 3/20 0.37
MEN1 O00255 3/20 0.37
CYP1A2 P05177 2/20 0.37
CYP3A4 P08684 2/20 0.37
MAPK1 P28482 2/20 0.37
BLM P54132 2/20 0.37
ATM Q13315 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
USP2 O75604 1/20 0.37
CYP2D6 P10635 1/20 0.37
MAPT P10636 1/20 0.37
LMNA P02545 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL221382 0.82 HSPA5 (0.64) HSPA5GAAKMT2AHIF1ACYP2C9
SCHEMBL10878501 0.77 HSPA5 (0.57) HSPA5GAAKMT2AHIF1ACYP2C9
SCHEMBL11015322 0.77 GAA (0.55) HSPA5GAAKMT2AHIF1ASMN1; SMN2
SCHEMBL14184185 0.76 GAA (0.56) HSPA5GAAKMT2AHIF1ACYP2C9
SCHEMBL29976141 0.76 HSPA5 (0.74) HSPA5GAAKMT2AHIF1ACYP2C9
SCHEMBL3138594 0.76 HSPA5 (0.74) HSPA5GAAKMT2AHIF1ACYP2C9
SCHEMBL10548217 0.75 LMNA (0.47) HSPA5GAAKMT2AHIF1ACYP2C9
SCHEMBL14586752 0.74 GAA (0.57) GAAKMT2AHIF1ACYP2C9CYP2C19
SCHEMBL7796135 0.73 HSPA5 (0.60) HSPA5GAAKMT2AHIF1ACYP2C9
SCHEMBL7248605 0.73 GAA (0.74) GAAKMT2AHIF1ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5990259-A Polyketone polymer composition SHELL OIL COMPANY (US) 1999-11-23 US disclosed