Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 12/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564652 | 1.00 | CAPN1 (0.47) | CAPN1CA1CA2CA7SMN1; SMN2 | |
| SCHEMBL8807825 | 0.96 | CAPN1 (0.44) | CAPN1CA1CA2CA7SMN1; SMN2 | |
| SCHEMBL8807411 | 0.90 | CA2 (0.52) | CAPN1CA1CA2CA7CA4 | |
| SCHEMBL8407770 | 0.89 | CAPN1 (0.48) | CAPN1CA1CA2CA7SMN1; SMN2 | |
| SCHEMBL8809904 | 0.89 | CAPN1 (0.48) | CAPN1CA1CA2CA7CA4 | |
| SCHEMBL8807363 | 0.89 | CAPN1 (0.60) | CAPN1CA1CA2CA7CA4 | |
| SCHEMBL8407938 | 0.88 | LARS1 (0.45) | CAPN1LARS1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8808500 | 0.88 | CAPN1 (0.41) | CAPN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8810468 | 0.87 | CAPN1 (0.46) | CAPN1CA1CA2CA7SMN1; SMN2 | |
| SCHEMBL8406492 | 0.87 | CAPN1 (0.48) | CAPN1SMN1; SMN2CA9ALDH1A1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925786-A1 | REMEDIES FOR ISCHEMIC DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-30 | — | — | EP | claimed |
| JP-10045584-A | — | — | None | — | — | JP | disclosed |
| JP-9169752-A | — | — | None | — | — | JP | disclosed |
| EP-0925786-A1 | REMEDIES FOR ISCHEMIC DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-30 | — | — | EP | disclosed |
| JP-H1045584-A | PLATELET AGGREGATION INHIBITOR | MITSUBISHI CHEM CORP | 1998-02-17 | — | — | JP | disclosed |
| EP-0810221-A1 | OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |
| JP-H09169752-A | OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVE | MITSUBISHI CHEM CORP | 1997-06-30 | — | — | JP | disclosed |