Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 4/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | MMP7 | P09237 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807411 | 0.90 | CA2 (0.52) | CAPN1CA2CA1CA9CA4 | |
| SCHEMBL8807363 | 0.89 | CAPN1 (0.60) | CAPN1CA2CA1CA9CA4 | |
| SCHEMBL8809904 | 0.89 | CAPN1 (0.48) | CAPN1CA2CA1CA9CA4 | |
| SCHEMBL8564652 | 0.89 | CAPN1 (0.47) | CAPN1CA2CA1CA9CA4 | |
| SCHEMBL8407579 | 0.89 | CAPN1 (0.47) | CAPN1CA2CA1CA9CA4 | |
| SCHEMBL8810468 | 0.88 | CAPN1 (0.46) | CAPN1CA2CA1CA9CA4 | |
| SCHEMBL8406492 | 0.88 | CAPN1 (0.48) | CAPN1CA9MMP2MMP1MMP3 | |
| SCHEMBL8807825 | 0.85 | CAPN1 (0.44) | CAPN1CA2CA1CA9CA4 | |
| SCHEMBL8808038 | 0.84 | CTSL (0.43) | CAPN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8406510 | 0.84 | MMP2 (0.38) | CAPN1CA2CA1CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925786-A1 | REMEDIES FOR ISCHEMIC DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-30 | — | — | EP | disclosed |
| EP-0810221-A1 | OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |