Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 5/20 | 0.44 |
| ▸ | CAPNS1 | P04632 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808948 | 0.90 | CAPN1 (0.44) | CAPN1CAPNS1POLBRAB9AMAPT | |
| SCHEMBL8407418 | 0.85 | CAPN1 (0.47) | CAPN1CAPNS1POLBTP53LMNA | |
| SCHEMBL8407953 | 0.84 | CAPN1 (0.61) | CAPN1CAPNS1NPC1 | |
| SCHEMBL8407942 | 0.84 | CAPN1 (0.61) | CAPN1CAPNS1NPC1 | |
| SCHEMBL8810066 | 0.82 | CAPN1 (0.47) | CAPN1CAPNS1LMNARAB9AMAPT | |
| SCHEMBL8404222 | 0.81 | CAPN1 (0.47) | CAPN1CAPNS1POLBLMNARAB9A | |
| SCHEMBL8406495 | 0.80 | CAPN1 (0.51) | CAPN1CAPNS1PSMB5 | |
| SCHEMBL8810895 | 0.79 | CAPN1 (0.55) | CAPN1CAPNS1RAB9ANPC1 | |
| SCHEMBL8809938 | 0.79 | CAPN1 (0.41) | CAPN1CAPNS1 | |
| SCHEMBL8404245 | 0.78 | CAPN1 (0.42) | CAPN1CAPNS1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925786-A1 | REMEDIES FOR ISCHEMIC DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-30 | — | — | EP | disclosed |
| EP-0810221-A1 | OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |