Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 6/20 | 0.44 |
| ▸ | CAPNS1 | P04632 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407947 | 0.90 | CAPN1 (0.44) | CAPN1CAPNS1NPC1RAB9AMAPT | |
| SCHEMBL8807996 | 0.85 | CAPN1 (0.50) | CAPN1CAPNS1CCR1GAANPC1 | |
| SCHEMBL8810066 | 0.84 | CAPN1 (0.47) | CAPN1CAPNS1NPC1RAB9AMAPT | |
| SCHEMBL8808955 | 0.84 | CAPN1 (0.62) | CAPN1CAPNS1CCR1GAAATM | |
| SCHEMBL8808938 | 0.84 | CAPN1 (0.62) | CAPN1CAPNS1CCR1GAAATM | |
| SCHEMBL8809938 | 0.83 | CAPN1 (0.41) | CAPN1CAPNS1GAA | |
| SCHEMBL8404222 | 0.82 | CAPN1 (0.47) | CAPN1CAPNS1CCR1NPC1RAB9A | |
| SCHEMBL8406495 | 0.81 | CAPN1 (0.51) | CAPN1CAPNS1 | |
| SCHEMBL8404245 | 0.78 | CAPN1 (0.42) | CAPN1CAPNS1SMN1; SMN2 | |
| SCHEMBL8811439 | 0.77 | CAPN1 (0.44) | CAPN1CAPNS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810221-A1 | OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |