Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.47 |
| ▸ | CAPNS1 | P04632 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.37 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.37 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.37 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.37 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.37 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.37 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.37 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.37 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810066 | 0.91 | CAPN1 (0.47) | CAPN1CAPNS1TAS1R3TAS1R1LMNA | |
| SCHEMBL8404255 | 0.85 | HTT (0.46) | CAPN1CAPNS1CCR1HTTPOLB | |
| SCHEMBL8404224 | 0.83 | CAPN1 (0.65) | CAPN1CAPNS1CCR1 | |
| SCHEMBL8404221 | 0.83 | CAPN1 (0.65) | CAPN1CAPNS1CCR1 | |
| SCHEMBL8406510 | 0.83 | MMP2 (0.38) | CAPN1CAPNS1HTTLMNAALDH1A1 | |
| SCHEMBL8808948 | 0.82 | CAPN1 (0.44) | CAPN1CAPNS1CCR1POLBP2RX7 | |
| SCHEMBL8407947 | 0.81 | CAPN1 (0.44) | CAPN1CAPNS1HTTPOLBPSMB5 | |
| SCHEMBL8809938 | 0.80 | CAPN1 (0.41) | CAPN1CAPNS1TAS1R3TAS1R1MAPK1 | |
| SCHEMBL8808907 | 0.78 | CAPN1 (0.43) | CAPN1CAPNS1PSMB1PSMB5PSMB2 | |
| SCHEMBL8406495 | 0.78 | CAPN1 (0.51) | CAPN1CAPNS1PSMB1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925786-A1 | REMEDIES FOR ISCHEMIC DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-30 | — | — | EP | disclosed |
| EP-0810221-A1 | OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |