Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | FSHR | P23945 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043959 | 0.95 | HDAC6 (0.43) | HDAC6HTTHDAC2HDAC8TTR | |
| SCHEMBL8408950 | 0.92 | TTR (0.41) | HDAC6HDAC2HDAC8TTRLMNA | |
| SCHEMBL8056945 | 0.89 | TTR (0.44) | HDAC6HDAC2HDAC8TTRALDH1A1 | |
| SCHEMBL8406921 | 0.88 | NPC1 (0.46) | MAP3K7HDAC6HTTHDAC2HDAC8 | |
| SCHEMBL8408911 | 0.85 | NR1H4 (0.40) | MAP3K7HDAC6HTTHDAC2HDAC8 | |
| SCHEMBL8409285 | 0.85 | MAP3K7 (0.39) | MAP3K7HDAC6HTTHDAC2HDAC8 | |
| SCHEMBL8406942 | 0.85 | MAP3K7 (0.39) | MAP3K7HDAC6HTTHDAC2HDAC8 | |
| SCHEMBL9408839 | 0.83 | NPC1 (0.41) | TTRALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL8043981 | 0.82 | NPC1 (0.50) | HDAC6HTTHDAC2HDAC8TTR | |
| SCHEMBL8061717 | 0.80 | TTR (0.42) | HDAC6HTTHDAC2HDAC8TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935900-A | BENZOTRIAZOLE COMPOUND, DIPHENYLSULFONE ELECTRON ACCEPTOR | OJL PAPER CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |