Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043958 | 0.95 | TTR (0.42) | HTTTTRLMNAGAAKMT2A | |
| SCHEMBL8409160 | 0.92 | TTR (0.40) | TTRLMNAKMT2ATP53MAPT | |
| SCHEMBL8406942 | 0.92 | MAP3K7 (0.39) | MAP3K7HTTTTRLMNAGAA | |
| SCHEMBL8055374 | 0.89 | TTR (0.44) | TTRLMNAKMT2AALDH1A1TP53 | |
| SCHEMBL8406921 | 0.87 | NPC1 (0.46) | MAP3K7HTTTTRLMNAGAA | |
| SCHEMBL8043973 | 0.86 | HTT (0.40) | HTTTTRLMNAGAAKMT2A | |
| SCHEMBL8408063 | 0.85 | MAP3K7 (0.42) | MAP3K7HTTTTRLMNAGAA | |
| SCHEMBL8408911 | 0.85 | NR1H4 (0.40) | MAP3K7HTTTTRLMNAGAA | |
| SCHEMBL8407973 | 0.84 | TTR (0.38) | TTRLMNAKMT2AMAPTPOLB | |
| SCHEMBL9408813 | 0.83 | NPC1 (0.40) | TTRLMNAKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935900-A | BENZOTRIAZOLE COMPOUND, DIPHENYLSULFONE ELECTRON ACCEPTOR | OJL PAPER CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |