Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.39 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408950 | 0.95 | TTR (0.41) | TTRLMNAMAPK1NLRP1SMN1; SMN2 | |
| SCHEMBL8043959 | 0.93 | HDAC6 (0.43) | TTRLMNASMN1; SMN2HDAC6HDAC2 | |
| SCHEMBL9408839 | 0.90 | NPC1 (0.41) | TTRLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8408063 | 0.89 | MAP3K7 (0.42) | TTRLMNAHDAC6HDAC2HDAC8 | |
| SCHEMBL8043991 | 0.86 | NPC1 (0.52) | TTRLMNASMN1; SMN2HDAC1NPC1 | |
| SCHEMBL31192002 | 0.84 | NPC1 (0.49) | LMNAMAPK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11315775 | 0.84 | NPC1 (0.49) | LMNAMAPK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8061576 | 0.83 | LMNA (0.47) | TTRLMNASMN1; SMN2HDAC6HDAC8 | |
| SCHEMBL8055374 | 0.83 | TTR (0.44) | TTRLMNASMN1; SMN2HDAC1NPC1 | |
| SCHEMBL8061708 | 0.83 | TTR (0.41) | TTRLMNAMAPK1SMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826511-B1 | Heat sensitive recording material | OJI PAPER CO (JP) | 2000-05-24 | — | — | EP | disclosed |
| EP-0826511-A1 | Heat sensitive recording material | Oji Paper Co., Ltd. (JP) | 1998-03-04 | — | — | EP | disclosed |