Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL767125 | 0.87 | CTNNB1 (0.65) | KMT2AMEN1MAPTLMNAHPGD | |
| SCHEMBL9724321 | 0.85 | KMT2A (0.63) | KMT2AMEN1MAPTLMNAESR1 | |
| SCHEMBL9010699 | 0.85 | KMT2A (0.72) | KMT2AMEN1MAPTLMNAESR1 | |
| SCHEMBL4382990 | 0.85 | CYP1A2 (0.65) | KMT2AMEN1MAPTLMNAESR1 | |
| SCHEMBL8408147 | 0.85 | CTNNB1 (0.57) | KMT2AMEN1MAPTLMNAHSD17B10 | |
| SCHEMBL8648432 | 0.84 | CTNNB1 (0.55) | KMT2AMEN1MAPTLMNAESR1 | |
| SCHEMBL2355280 | 0.82 | CTNNB1 (0.58) | KMT2AMEN1MAPTLMNAESR1 | |
| SCHEMBL10919302 | 0.82 | CTNNB1 (0.58) | KMT2AMEN1MAPTLMNAHPGD | |
| SCHEMBL4384831 | 0.82 | CYP1A2 (0.62) | KMT2AMEN1MAPTHPGDHSD17B10 | |
| SCHEMBL5929171 | 0.81 | NPSR1 (0.78) | KMT2AMEN1MAPTHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030194385-A1 | PHARMACEUTICAL FORMULATIONS CONTAINING SOLUBILIZED HYDROQUINONE, SALICYLIC ACID AND HYDROCORTISONE FOR THE TREATMENT OF MELASMA AND RELATED DERMATOLOGICAL PROBLEMS | LILA GRUBER RESEARCH FOUNDATION (US) | 2003-10-16 | — | — | US | disclosed |
| CN-1137556-A | Modified gas desulfurization method | WEI XIONGHUI (CN) | 1996-12-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030194385-A1 | PHARMACEUTICAL FORMULATIONS CONTAINING SOLUBILIZED HYDROQUINONE, SALICYLIC ACID AND HYDROCORTISONE FOR THE TREATMENT OF MELASMA AND RELATED DERMATOLOGICAL PROBLEMS | MC1R, MC2R, HMGCR | KMT2A 1424/4885MEN1 605/4885MAPT 3402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.