SCHEMBL8408204

SCHEMBL8408204

COc1cccc(C(C)(C)c2cccc(OC)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.52
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP3A4 P08684 1/20 0.50
KIF11 P52732 1/20 0.47
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
ENPP2 Q13822 1/20 0.45
CA4 P22748 1/20 0.44
CHRM5 P08912 1/20 0.44
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31476373 0.89 MAOB (0.49) ACHECA1CA2CA7CA9
SCHEMBL31476423 0.89 CYP3A4 (0.66) ACHECA1CA2CA7CA9
SCHEMBL146154 0.86 ACHE (0.52) ACHECA1CA2CA7CA9
Hydrochloric Acid SCHEMBL29893927 0.84 ACHE (0.50) ACHECA1CA2CA7CA9
SCHEMBL19700476 0.84 ESR1 (0.43) ACHECA1CA2CA7CA9
SCHEMBL16396186 0.84 P4HB (0.46) ACHECA1CA2CA7CA9
SCHEMBL23344383 0.83 MAPT (0.40) ACHECA1CA2CA7CA9
SCHEMBL10112754 0.83 ESR1 (0.59) ACHECA1CA2CA7CA9
SCHEMBL2145301 0.83 ACHE (0.48) ACHECA1CA2CA7CA9
SCHEMBL8367527 0.83 ACHE (0.48) ACHECA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140153086-A1 POLYIMIDE OPTICAL ARTICLES HAVING SELECTIVE TRANSMITTANCE PROPERTIES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-06-05 US disclosed
US-20140153086-A1 POLYIMIDE OPTICAL ARTICLES HAVING SELECTIVE TRANSMITTANCE PROPERTIES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-06-05 US disclosed
WO-2014085531-A1 POLYIMIDE OPTICAL ARTICLES HAVING SELECTIVE TRANSMITTANCE PROPERTIES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-06-05 WO disclosed
US-8274744-B2 Polyimide optical article SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-09-25 US disclosed
US-8274744-B2 Polyimide optical article SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-09-25 US disclosed
US-20120127565-A1 POLYIMIDE OPTICAL ARTICLE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-05-24 US disclosed
US-20120127565-A1 POLYIMIDE OPTICAL ARTICLE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-05-24 US disclosed
WO-2012068439-A1 OPTICAL ARTICLE WITH LENS COMPRISING POLYIMIDE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-05-24 WO disclosed
US-4781963-A POLYESTER FILM, ORGANIC CARBOXYLIC ACID LUBRICANT DIAFOIL COMPANY, LIMITED (JP) 1988-11-01 US disclosed