SCHEMBL442916

SCHEMBL442916

Oc1ccc(-c2ccc(O)c3ccccc23)c2ccccc12

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 8/20 0.81
EP300 Q09472 2/20 0.59
KAT2B Q92831 2/20 0.59
KAT8 Q9H7Z6 2/20 0.59
HDAC3 O15379 1/20 0.59
NCOR2 Q9Y618 1/20 0.59
MAPT P10636 2/20 0.50
HPGD P15428 2/20 0.50
ALOX15 P16050 2/20 0.50
RECQL P46063 2/20 0.50
HSD17B10 Q99714 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
CYP1A2 P05177 1/20 0.50
APP P05067 1/20 0.50
THRB P10828 1/20 0.50
TSHR P16473 1/20 0.50
CASP1 P29466 1/20 0.50
SNCA P37840 1/20 0.50
LDHA P00338 1/20 0.50
CTSB P07858 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13265824 1.00 IDO1 (0.81) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL29638 0.90 IDO1 (1.00) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL32677325 0.90 IDO1 (1.00) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL29362983 0.90 IDO1 (1.00) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL30827114 0.85 CYP1A2 (0.62) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL11504207 0.85 CYP1A2 (0.62) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL9721905 0.84 IDO1 (0.87) IDO1EP300KAT2BKAT8HDAC3
Catechol SCHEMBL9720436 0.84 IDO1 (0.87) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL1889602 0.84 IDO1 (0.65) IDO1EP300KAT2BKAT8HDAC3
SCHEMBL20599884 0.83 IDO1 (0.56) IDO1EP300KAT2BKAT8HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5447989-A Impact modifier is variation of core-shell polymer, shell is discontinuous ENICHEM S.P.A. (IT) 1995-09-05 US claimed
US-4804415-A COUPLING AROMATIC DIAZONIUM COMPOUND WITH 3-HYDROXY-2-NAPHTHOIC AICD AND BINAPHTHOL KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1989-02-14 US claimed
JP-1066231-A None JP disclosed
US-20230275251-A1 CROSSOVER RESISTANT MATERIALS FOR AQUEOUS ORGANIC REDOX FLOW BATTERIES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2023-08-31 US disclosed
US-20230275251-A1 CROSSOVER RESISTANT MATERIALS FOR AQUEOUS ORGANIC REDOX FLOW BATTERIES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2023-08-31 US disclosed
US-11646434-B2 Crossover resistant materials for aqueous organic redox flow batteries UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2023-05-09 US disclosed
US-11646434-B2 Crossover resistant materials for aqueous organic redox flow batteries UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2023-05-09 US disclosed
US-20210005918-A1 CROSSOVER RESISTANT MATERIALS FOR AQUEOUS ORGANIC REDOX FLOW BATTERIES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2021-01-07 US disclosed
US-20200148541-A1 AN APPROACH TO A BOTTOM-UP SYNTHESIS OF NANOCARBONS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2020-05-14 US disclosed
US-20200148541-A1 AN APPROACH TO A BOTTOM-UP SYNTHESIS OF NANOCARBONS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2020-05-14 US disclosed
US-10283777-B2 Secondary battery RICOH COMPANY, LTD. (JP) 2019-05-07 US disclosed
US-4097461-A Oxidative coupling of alkylphenols or 1-naphthols catalyzed by metal complexes of diketo compounds ICI AMERICAS INC. (US) 1978-06-27 US disclosed
US-4096190-A Oxidative coupling of alkylphenols catalyzed by metal ammonia complexes ICI AMERICAS INC. (US) 1978-06-20 US disclosed
US-4085124-A Oxidative coupling of alkylphenols, alkoxyphenols and 1-naphthols catalyzed by metal complexes of amino compounds ICI AMERICAS INC. (US) 1978-04-18 US disclosed
US-4070383-A COPPER COMPOUND-ANIONIC SURFACTANT-ALKALI METAL COMPOUND CATALYST SYSTEM ICI AMERICAS INC. (US) 1978-01-24 US disclosed
US-4067890-A Oxidative coupling of alkylphenols, alkoxyphenols and naphthols catalyzed by metal complexes of amino carboxylic and amino sulfonic acids ICI AMERICA INC. (US) 1978-01-10 US disclosed
US-3976488-A COUPLER, EXTENDER, DISPERSION MEDIUM MITA INDUSTRIAL COMPANY, LTD. (JA) 1976-08-24 US disclosed
US-3950171-A THERMOPLASTIC RESIN DIAZONIUM SALT MITA INDUSTRIAL CO. LTD. (JA) 1976-04-13 US disclosed
US-3948661-A Process for diazo-type multicolor reproduction MITA INDUSTRIAL COMPANY LTD. (JA) 1976-04-06 US disclosed
US-3944422-A Photosensitive material in use for diazo-type multicolor reproduction MITA INDUSTRIAL COMPANY LIMITED (JA) 1976-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200148541-A1 AN APPROACH TO A BOTTOM-UP SYNTHESIS OF NANOCARBONS TYMS, NCL, PFAS IDO1 1705/4885EP300 4318/4885KAT2B 2577/4885
US-20230275251-A1 CROSSOVER RESISTANT MATERIALS FOR AQUEOUS ORGANIC REDOX FLOW BATTERIES SLC25A21, SLC25A11, SLC26A3 IDO1 4372/4885EP300 3526/4885KAT2B 1400/4885
US-20210005918-A1 CROSSOVER RESISTANT MATERIALS FOR AQUEOUS ORGANIC REDOX FLOW BATTERIES SLC25A21, SLC25A11, SLC26A3 IDO1 4372/4885EP300 3526/4885KAT2B 1400/4885
US-11646434-B2 Crossover resistant materials for aqueous organic redox flow batteries SLC25A21, SLC25A11, SLC26A3 IDO1 4372/4885EP300 3526/4885KAT2B 1400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.