Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | ADK | P55263 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408445 | 0.78 | SLC6A4 (0.38) | KDM4EMAPK1CTDSP1MAPTSMN1; SMN2 | |
| SCHEMBL8409441 | 0.76 | SMN1; SMN2 (0.36) | KDM4EMAPK1CTDSP1MAPTNPC1 | |
| SCHEMBL8408559 | 0.73 | HTR2C (0.31) | KDM4EMAPK1MAPTSLC6A4L3MBTL1 | |
| SCHEMBL8406468 | 0.68 | ALDH1A1 (0.34) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| Anthracene SCHEMBL11852092 | 0.64 | KDM4E (0.48) | KDM4EMAPK1TDP1MAPTNPC1 | |
| SCHEMBL31375013 | 0.64 | KDM4E (0.82) | KDM4EMAPK1TDP1MAPTNPC1 | |
| SCHEMBL16594922 | 0.63 | KDM4E (0.49) | KDM4EMAPK1TDP1MAPTNPC1 | |
| SCHEMBL16594736 | 0.63 | KDM4E (0.49) | KDM4EMAPK1TDP1MAPTNPC1 | |
| Anthracene SCHEMBL11854178 | 0.63 | KDM4E (0.47) | KDM4EMAPK1TDP1MAPTNPC1 | |
| SCHEMBL10053031 | 0.62 | SLC6A4 (0.42) | KDM4ETDP1SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663206-B1 | Naphthalenmethylenemalonic diesters, and UV absorbers and cosmetic compositions containing the diesters | KAO CORP (JP) | 1999-07-14 | — | — | EP | disclosed |
| US-5508025-A | SUNSCREEN AGENTS | KAO CORPORATION (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0663206-A1 | Naphthalenmethylenemalonic diesters, and UV absorbers and cosmetic compositions containing the diesters | Kao Corporation (JP) | 1995-07-19 | — | — | EP | disclosed |