Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3229576 | 0.80 | ELANE (0.46) | HTTKMT2ASMN1; SMN2ELANE | |
| SCHEMBL8409441 | 0.80 | SMN1; SMN2 (0.36) | SLC6A4KDM4EMAPTMAPK1L3MBTL1 | |
| SCHEMBL8406468 | 0.79 | ALDH1A1 (0.34) | SLC6A4DRD2KDM4EMAPTL3MBTL1 | |
| SCHEMBL8408560 | 0.78 | KDM4E (0.35) | SLC6A4KDM4EMAPTMAPK1L3MBTL1 | |
| SCHEMBL8408559 | 0.77 | HTR2C (0.31) | SLC6A4KDM4EMAPTMAPK1L3MBTL1 | |
| SCHEMBL9246592 | 0.75 | CDK1 (0.44) | KDM4EGSK3B | |
| SCHEMBL8104489 | 0.74 | SIRT1 (0.40) | KDM4EMAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL8406335 | 0.73 | ELANE (0.47) | SLC6A4DRD2KDM4EMAPTMAPK1 | |
| SCHEMBL10053031 | 0.70 | SLC6A4 (0.42) | SLC6A4DRD2KDM4ESLC6A2SLC6A3 | |
| SCHEMBL11322478 | 0.67 | SLC6A2 (0.38) | SLC6A4DRD2KDM4ESLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663206-B1 | Naphthalenmethylenemalonic diesters, and UV absorbers and cosmetic compositions containing the diesters | KAO CORP (JP) | 1999-07-14 | — | — | EP | disclosed |
| US-5508025-A | SUNSCREEN AGENTS | KAO CORPORATION (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0663206-A1 | Naphthalenmethylenemalonic diesters, and UV absorbers and cosmetic compositions containing the diesters | Kao Corporation (JP) | 1995-07-19 | — | — | EP | disclosed |