Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408615 | 1.00 | HRH3 (0.57) | HRH3KCNH2ALDH1A1RAB9ANPSR1 | |
| SCHEMBL8411748 | 0.82 | ALDH1A1 (0.47) | HRH3KCNH2ALDH1A1RAB9ANPSR1 | |
| SCHEMBL8408638 | 0.82 | ALDH1A1 (0.47) | HRH3KCNH2ALDH1A1RAB9ANPSR1 | |
| SCHEMBL11102035 | 0.81 | KCNH2 (0.56) | HRH3KCNH2ALDH1A1TNKSPARP1 | |
| SCHEMBL8408982 | 0.81 | ALDH1A1 (0.61) | HRH3KCNH2ALDH1A1RAB9ANPSR1 | |
| SCHEMBL4468612 | 0.72 | HRH3 (0.98) | HRH3KCNH2ADRA1A | |
| SCHEMBL2009260 | 0.71 | HRH3 (0.72) | HRH3KCNH2ADRA1A | |
| SCHEMBL2569436 | 0.71 | HRH3 (0.45) | HRH3KCNH2ALDH1A1RAB9ANPSR1 | |
| SCHEMBL8409027 | 0.71 | ESR1 (0.72) | HRH3KCNH2ALDH1A1RAB9ANPSR1 | |
| SCHEMBL31277481 | 0.70 | ALDH1A1 (0.95) | HRH3KCNH2ALDH1A1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948775-A | OSTEOPOROSIS; ANTICANCER AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-09-07 | — | — | US | disclosed |