Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.49 |
| ▸ | G6PD | P11413 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409027 | 0.86 | ESR1 (0.72) | ALDH1A1RAB9ANPSR1HRH3KCNH2 | |
| SCHEMBL8408698 | 0.81 | HRH3 (0.57) | ALDH1A1RAB9ANPSR1HRH3KCNH2 | |
| SCHEMBL8408615 | 0.81 | HRH3 (0.57) | ALDH1A1RAB9ANPSR1HRH3KCNH2 | |
| SCHEMBL31277481 | 0.74 | ALDH1A1 (0.95) | ALDH1A1RAB9ANPSR1HRH3KCNH2 | |
| SCHEMBL11104386 | 0.73 | ADRB1 (0.62) | HRH3KCNH2ADRA1APOLBRXFP1 | |
| SCHEMBL4485049 | 0.72 | HRH3 (1.00) | HRH3KCNH2ADRA1A | |
| SCHEMBL1663473 | 0.72 | LMNA (0.63) | ALDH1A1RAB9ANPSR1HRH3KCNH2 | |
| SCHEMBL11099494 | 0.72 | ADRB1 (0.61) | HRH3KCNH2ADRA1APOLBRXFP1 | |
| SCHEMBL8411748 | 0.72 | ALDH1A1 (0.47) | ALDH1A1RAB9ANPSR1HRH3KCNH2 | |
| SCHEMBL8408638 | 0.72 | ALDH1A1 (0.47) | ALDH1A1RAB9ANPSR1HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948775-A | OSTEOPOROSIS; ANTICANCER AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-09-07 | — | — | US | disclosed |