Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14499024 | 0.79 | PPARG (0.41) | KCNH2PPARGGABRA1GABRG2GABRB3 | |
| SCHEMBL4750814 | 0.76 | PPARG (0.41) | KCNH2PPARGGABRA1GABRG2GABRB3 | |
| SCHEMBL14305744 | 0.76 | KCNH2 (0.46) | KCNH2PPARGGABRA1GABRG2GABRB3 | |
| SCHEMBL19862547 | 0.75 | KCNH2 (0.44) | KCNH2SMN1; SMN2KMT2AMEN1OPRM1 | |
| SCHEMBL4314841 | 0.74 | KCNH2 (0.47) | KCNH2SMN1; SMN2KMT2AMEN1OPRM1 | |
| SCHEMBL11991705 | 0.74 | NOS2 (0.44) | KCNH2SMN1; SMN2KMT2AMEN1OPRM1 | |
| SCHEMBL14306289 | 0.74 | KCNH2 (0.53) | KCNH2PPARGGABRA1GABRG2GABRB3 | |
| SCHEMBL681576 | 0.74 | KCNH2 (0.49) | KCNH2PPARGGABRA1GABRG2GABRB3 | |
| SCHEMBL5659035 | 0.74 | KCNH2 (0.41) | KCNH2PPARGGABRA1GABRG2GABRB3 | |
| SCHEMBL8234820 | 0.73 | KCNH2 (0.47) | KCNH2PPARGGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | disclosed |