Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.60 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.60 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882317 | 0.87 | F10 (0.57) | F10SIRT2SIRT1SIRT3 | |
| SCHEMBL5249717 | 0.81 | NR1H4 (0.65) | SIRT2 | |
| SCHEMBL8529894 | 0.80 | RAB9A (0.70) | SMN1; SMN2 | |
| SCHEMBL4883970 | 0.80 | NR1H4 (0.53) | F10 | |
| SCHEMBL12250976 | 0.80 | NPSR1 (0.58) | F10SMN1; SMN2 | |
| SCHEMBL28390021 | 0.80 | MEN1 (0.71) | SIRT2 | |
| SCHEMBL9097751 | 0.80 | F10 (0.52) | F10 | |
| SCHEMBL1613254 | 0.80 | RAB9A (0.51) | F10SMN1; SMN2SIRT2SIRT1SIRT3 | |
| SCHEMBL12302912 | 0.79 | MTNR1A (0.73) | SMN1; SMN2 | |
| SCHEMBL8119011 | 0.79 | SIRT2 (0.64) | SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883106-A | 5-lipoxygenase inhibitors | PFIZER INC. (US) | 1999-03-16 | — | — | US | disclosed |