Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.61 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408934 | 0.99 | ALOX5 (0.60) | ALOX5GRM5CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL7811046 | 0.81 | ALOX5 (0.86) | ALOX5GRM5CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL7809126 | 0.81 | ALOX5 (0.84) | ALOX5GRM5CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL7802752 | 0.79 | ALOX5 (0.85) | ALOX5GRM5CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL7802468 | 0.79 | ALOX5 (0.84) | ALOX5GRM5CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL8781540 | 0.77 | ALOX5 (0.55) | ALOX5GRM5CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL7815037 | 0.76 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL8781543 | 0.75 | ALOX5 (0.61) | ALOX5GRM5CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL7811849 | 0.75 | ALOX5 (0.81) | ALOX5GRM5CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL7807535 | 0.74 | ALOX5 (0.87) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883106-A | 5-lipoxygenase inhibitors | PFIZER INC. (US) | 1999-03-16 | — | — | US | disclosed |