Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PLEC | Q15149 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 4/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL840931 | 0.83 | KDM4A (0.44) | USP2ESR1ESR2ALDH1A1HPGD | |
| SCHEMBL841016 | 0.83 | MEN1 (0.60) | MEN1KMT2APOLBUSP2ATM | |
| SCHEMBL21974398 | 0.74 | MEN1 (0.38) | MEN1KMT2APOLBUSP2ATM | |
| SCHEMBL12708320 | 0.69 | MEN1 (0.68) | MEN1KMT2APOLBUSP2ATM | |
| SCHEMBL23941076 | 0.68 | HSD17B10 (0.49) | MEN1KMT2APOLBUSP2ATM | |
| SCHEMBL23941083 | 0.68 | USP2 (0.41) | MEN1KMT2APOLBUSP2ATM | |
| SCHEMBL840985 | 0.68 | USP2 (0.59) | MEN1KMT2APOLBUSP2ATM | |
| SCHEMBL15305308 | 0.67 | MEN1 (0.61) | MEN1KMT2APOLBUSP2ATM | |
| SCHEMBL14433567 | 0.67 | MEN1 (0.68) | MEN1KMT2APOLBUSP2ATM | |
| SCHEMBL23941086 | 0.67 | ALDH1A1 (0.41) | MEN1KMT2APOLBUSP2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143069-B2 | useful for selective measurement of hypochlorite ion; does not react with hydrogen peroxide which is a weakly reactive oxygen species, and does not induce increase of fluorescence with hydroxyl radical or peroxynitrite which are reactive oxygen species having high activity | THE UNIVERSITY OF TOKYO (JP) | 2012-03-27 | — | — | US | disclosed |
| US-20090317914-A1 | FLUORESCENT PROBE | THE UNIVERSITY OF TOKYO (JP) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090317914-A1 | FLUORESCENT PROBE | H1-10, H1-0, NHERF1 | MEN1 444/4885KMT2A 2962/4885POLB 1720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.