Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16044746 | 0.86 | ALDH1A1 (0.40) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29415231 | 0.86 | ALDH1A1 (0.40) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8757109 | 0.82 | HSD11B1 (0.38) | HSD11B1PGRKDM4ECYP1A2CYP3A4 | |
| SCHEMBL8412725 | 0.81 | KMT2A (0.42) | HSD11B1HTR6ALDH1A1KMT2A | |
| SCHEMBL4936612 | 0.78 | MEN1 (0.44) | HSD11B1KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL197651 | 0.78 | ALDH1A1 (0.46) | HSD11B1KDM4EGAATSHRALDH1A1 | |
| SCHEMBL198294 | 0.78 | HSD11B1 (0.46) | HSD11B1PGRKDM4ECYP1A2CYP3A4 | |
| SCHEMBL8634554 | 0.77 | HSD11B1 (0.46) | HSD11B1PGRKDM4ECYP1A2CYP3A4 | |
| SCHEMBL20414679 | 0.77 | CA1 (0.50) | HSD11B1L3MBTL1KMT2A | |
| SCHEMBL28520000 | 0.77 | GAA (0.52) | CYP3A4CYP2C9HTR6GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1339432-A | Extracting method for substituted phenyl compounds | ROHM & HAAS (US) | 2002-03-13 | — | — | CN | disclosed |
| CN-1070175-C | Process for the preparation of 2, 6-disubstituted benzenesulfonates or 2, 6-disubstituted benzenesulfonates further substituted in the 3-, 4-or 5-position | ROHM & HAAS (US) | 2001-08-29 | — | — | CN | disclosed |
| EP-0708087-B1 | Method for making a substituted benzene compound | ROHM & HAAS (US) | 1999-07-28 | — | — | EP | disclosed |
| CN-1174189-A | Process for preparing substituted benzene compounds | ROHM & HAAS (US) | 1998-02-25 | — | — | CN | disclosed |
| US-5717124-A | Process for preparation of oxyglutaric acid ester derivatives | UBE INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| US-5670691-A | REACTION OF 2-SUBSTITUTED BENZENESULFONATE WITH LITHIUM COMPOUND THEN REACTION WITH ELECTROPHILE TO FORM 2,6-DISUBSTITUTED BENZENESULFONATE | ROHM AND HAAS COMPANY (US) | 1997-09-23 | — | — | US | disclosed |
| EP-0708087-A1 | Method for making a substituted benzene compound | ROHM AND HAAS COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |