SCHEMBL8409306

SCHEMBL8409306

COCCOCCOC(=O)CC(=O)OCCOCCOC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 2/20 0.44
GAA P10253 2/20 0.44
SI P14410 2/20 0.44
MGAM2 Q2M2H8 2/20 0.44
TSHR P16473 7/20 0.41
ABCB11 O95342 1/20 0.41
CYP3A4 P08684 1/20 0.41
ADRA2B P18089 1/20 0.41
OPRD1 P41143 1/20 0.41
SCN5A Q14524 1/20 0.41
ALDH1A1 P00352 3/20 0.38
TP53 P04637 2/20 0.38
HIF1A Q16665 2/20 0.38
HSD17B10 Q99714 2/20 0.38
THRB P10828 1/20 0.38
DGKA P23743 1/20 0.35
CA2 P00918 1/20 0.35
EPHX2 P34913 2/20 0.33
ADRA2A P08913 1/20 0.33
ADRA1A P35348 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL813498 0.93 MGAM (0.50) MGAMGAASIMGAM2TSHR
SCHEMBL15335273 0.92 MEN1 (0.44) MGAMGAASIMGAM2TSHR
SCHEMBL10354582 0.89 MGAM (0.50) MGAMGAASIMGAM2TSHR
SCHEMBL28329649 0.89 ABCB11 (0.38) MGAMGAASIMGAM2TSHR
SCHEMBL3914017 0.89 MGAM (0.50) MGAMGAASIMGAM2TSHR
SCHEMBL12727528 0.89 MGAM (0.50) MGAMGAASIMGAM2TSHR
SCHEMBL16368788 0.88 GAA (0.46) MGAMGAASIMGAM2TSHR
SCHEMBL27852722 0.88 MGAM (0.46) MGAMGAASIMGAM2TSHR
SCHEMBL22510580 0.86 ADRA2A (0.48) TSHRABCB11CYP3A4ADRA2BOPRD1
SCHEMBL13268865 0.86 ADRA2A (0.48) TSHRABCB11CYP3A4ADRA2BOPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8784990-B2 Adhesive film composition for glass lamination SK INNOVATION CO., LTD. (KR) 2014-07-22 US disclosed
US-8426507-B2 Composition of eco-friendly hot melt adhesive SK INNOVATION CO., LTD. (KR) 2013-04-23 US disclosed
US-8426507-B2 Composition of eco-friendly hot melt adhesive SK INNOVATION CO., LTD. (KR) 2013-04-23 US disclosed
US-20120165441-A1 Composition of Eco-Friendly Hot Melt Adhesive SK INNOVATION CO., LTD. (KR) 2012-06-28 US disclosed
US-20120157637-A1 Adhesive Film Composition for Glass Lamination SK INNOVATION CO., LTD. (KR) 2012-06-21 US disclosed
CN-102171213-A Pyrazolo [3, 4] pyrimidin-4-yl derivatives and their uses to treat diabetes and obesity ASTRAZENECA AB 2011-08-31 CN disclosed
EP-0663206-B1 Naphthalenmethylenemalonic diesters, and UV absorbers and cosmetic compositions containing the diesters KAO CORP (JP) 1999-07-14 EP disclosed
US-5508025-A SUNSCREEN AGENTS KAO CORPORATION (JP) 1996-04-16 US disclosed
EP-0663206-A1 Naphthalenmethylenemalonic diesters, and UV absorbers and cosmetic compositions containing the diesters Kao Corporation (JP) 1995-07-19 EP disclosed