Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3009732 | 0.86 | EPHX1 (0.44) | EPHX1THRBTSHRBTN3A1ALDH1A1 | |
| SCHEMBL587661 | 0.86 | THRB (0.57) | EPHX1THRBTSHRBTN3A1ALDH1A1 | |
| SCHEMBL10603946 | 0.80 | EPHX1 (0.41) | EPHX1THRBTSHRBTN3A1ALDH1A1 | |
| SCHEMBL10603950 | 0.80 | EPHX1 (0.41) | EPHX1THRBTSHRBTN3A1ALDH1A1 | |
| SCHEMBL1269971 | 0.80 | — | — | |
| SCHEMBL29001937 | 0.78 | ALDH1A1 (0.46) | EPHX1THRBTSHRBTN3A1ALDH1A1 | |
| SCHEMBL9540458 | 0.78 | — | — | |
| SCHEMBL9540463 | 0.78 | — | — | |
| SCHEMBL15282390 | 0.77 | EPHX1 (0.42) | EPHX1THRBTSHRBTN3A1ALDH1A1 | |
| SCHEMBL15281959 | 0.77 | EPHX1 (0.42) | EPHX1THRBTSHRBTN3A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663206-B1 | Naphthalenmethylenemalonic diesters, and UV absorbers and cosmetic compositions containing the diesters | KAO CORP (JP) | 1999-07-14 | — | — | EP | disclosed |
| EP-0663206-A1 | Naphthalenmethylenemalonic diesters, and UV absorbers and cosmetic compositions containing the diesters | Kao Corporation (JP) | 1995-07-19 | — | — | EP | disclosed |