SCHEMBL840939

SCHEMBL840939

CCCCCCCCCCCCCCCC(=O)NC(CN1CCOCC1)C(O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UGCG Q16739 9/20 1.00
KMT2A Q03164 3/20 1.00
MEN1 O00255 2/20 1.00
TP53 P04637 1/20 1.00
CYP3A4 P08684 1/20 1.00
CYP2D6 P10635 1/20 1.00
CYP2C9 P11712 1/20 1.00
NFKB1 P19838 1/20 1.00
MAPK1 P28482 1/20 1.00
CYP2C19 P33261 1/20 1.00
HIF1A Q16665 1/20 1.00
MAPT P10636 1/20 1.00
MTOR P42345 1/20 1.00
GMNN O75496 1/20 0.98
LMNA P02545 1/20 0.98
BLM P54132 1/20 0.98
PMP22 Q01453 1/20 0.98
SMN1; SMN2 Q16637 1/20 0.98
NPSR1 Q6W5P4 1/20 0.98
HTR1A P08908 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL363373 1.00 UGCG (1.00) UGCGKMT2AMEN1TP53CYP3A4
SCHEMBL14304968 1.00 UGCG (1.00) UGCGKMT2AMEN1TP53CYP3A4
SCHEMBL12000798 1.00 UGCG (1.00) UGCGKMT2AMEN1TP53CYP3A4
SCHEMBL5452846 1.00 UGCG (1.00) UGCGKMT2AMEN1TP53CYP3A4
SCHEMBL295573 1.00 UGCG (1.00) UGCGKMT2AMEN1TP53CYP3A4
SCHEMBL23845860 1.00 UGCG (1.00) UGCGKMT2AMEN1TP53CYP3A4
SCHEMBL137622 1.00 UGCG (1.00) UGCGKMT2AMEN1TP53CYP3A4
SCHEMBL723342 1.00 UGCG (1.00) UGCGKMT2AMEN1TP53CYP3A4
SCHEMBL13460643 1.00 UGCG (1.00) UGCGKMT2AMEN1TP53CYP3A4
SCHEMBL13460354 1.00 UGCG (1.00) UGCGKMT2AMEN1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12150969-B2 Synthetically enveloped virus University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2024-11-26 US claimed
EP-4384220-A2 COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER The Johns Hopkins University (US) 2024-06-19 EP claimed
WO-2023244470-A1 SURFACE CALR CHEMICAL INDUCERS THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2023-12-21 WO claimed
WO-2023019186-A2 COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER THE JOHNS HOPKINS UNIVERSITY (US) 2023-02-16 WO claimed
US-20220257604-A1 COMPOSITIONS AND METHODS FOR MODULATING VIRAL INFECTIONS BY REGULATING GLUCOSYLCERAMIDES UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2022-08-18 US claimed
US-20220062254-A1 INHIBITORS OF GANGLIOSIDES METABOLISM FOR THE TREATMENT OF MOTOR NEURON DISEASES ICM INST DU CERVEAU ET DE LA MOELLE EPINIERE (FR) 2022-03-03 US claimed
EP-3934688-A1 COMPOSITIONS AND METHODS FOR MODULATING VIRAL INFECTIONS BY REGULATING GLUCOSYLCERAMIDES University of Virginia Patent Foundation (US) 2022-01-12 EP claimed
US-11065238-B2 Inhibitors of gangliosides metabolism for the treatment of motor neuron diseases ICM (INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE) (FR) 2021-07-20 US claimed
US-20200316146-A1 SYNTHETICALLY ENVELOPED VIRUS PITTSBURGH, UNIVERSITY OF - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2020-10-08 US claimed
WO-2020185675-A1 COMPOSITIONS AND METHODS FOR MODULATING VIRAL INFECTIONS BY REGULATING GLUCOSYLCERAMIDES UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2020-09-17 WO claimed
WO-2001054654-A2 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 2001-08-02 WO claimed
WO-2001047513-A1 TREATMENT OF HYPERPROLIFERATIVE DISORDERS CHILDRENS HOSPITAL LOS ANGELES RESEARCH INSTITUTE (US) 2001-07-05 WO claimed
US-6235737-B1 APPLYING COMPOUND TO ADJUST CERAMIDE CONCENTRATION GILLETTE COMPANY, THE 2001-05-22 US claimed
EP-1098642-A1 METHODS FOR TREATING CONDITIONS MODULATED BY LACTOSYLCERAMIDE THE JOHNS HOPKINS UNIVERSITY (US) 2001-05-16 EP claimed
EP-1091745-A1 TREATMENT OF HYPERPROLIFERATIVE DISORDERS CHILDREN'S HOSPITAL OF LOS ANGELES (US) 2001-04-18 EP claimed
EP-0996433-A1 METHODS FOR TREATMENT OF CONDITIONS ASSOCIATED WITH LACTOSYLCERAMIDE THE JOHNS HOPKINS UNIVERSITY (US) 2000-05-03 EP claimed
WO-2000006145-A1 METHODS FOR TREATING CONDITIONS MODULATED BY LACTOSYLCERAMIDE JOHNS HOPKINS UNIVERSITY (US) 2000-02-10 WO claimed
WO-2000000207-A1 TREATMENT OF HYPERPROLIFERATIVE DISORDERS CHILDREN'S HOSPITAL OF LOS ANGELES (US) 2000-01-06 WO claimed
US-5976781-A DIAGNOSING MALARIA BY MIXING BLOOD WITH ENZYME INHIBITOR, DETERMINING ENZYME ACTIVITY, COMPARING TO CONTROL SAMPLE; PLASMODIUM ENZYME IS MORE SENSITIVE TO INHIBITION SO DEACTIVATION INDICATES DISEASE THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1999-11-02 US claimed
US-5863716-A Treatment of plasmodium THE LELAND STANFORD JUNIOR UNIVERSITY BOARD OF TRUSTEES (US) 1999-01-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12150969-B2 Synthetically enveloped virus PIGS, LIPG, FURIN UGCG 121/4885KMT2A 3109/4885MEN1 1457/4885
US-11065238-B2 Inhibitors of gangliosides metabolism for the treatment of motor neuron diseases GBA1, SMN1; SMN2, GAA UGCG 13/4885KMT2A 2710/4885MEN1 3980/4885
US-20200316146-A1 SYNTHETICALLY ENVELOPED VIRUS PIGS, LIPG, FURIN UGCG 121/4885KMT2A 3109/4885MEN1 1457/4885
US-20220062254-A1 INHIBITORS OF GANGLIOSIDES METABOLISM FOR THE TREATMENT OF MOTOR NEURON DISEASES GBA1, SMN1; SMN2, GAA UGCG 13/4885KMT2A 2710/4885MEN1 3980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.