SCHEMBL8409565

SCHEMBL8409565

COC1=C(c2ccccc2)C=CCC1=C=O

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 2/20 0.37
MITF O75030 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CA4 P22748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL27493739 0.65 BACE1 (0.31)
Hydrochloric Acid SCHEMBL8448476 0.64 ALDH1A1 (0.33) ALDH1A1
SCHEMBL15009103 0.63 CFTR (0.33) PDE4BALDH1A1MAPTHTT
SCHEMBL5892367 0.63 CFTR (0.39) ALDH1A1
SCHEMBL7638439 0.63 CFTR (0.39) ALDH1A1
Fluoride Ion SCHEMBL1130346 0.62 ALDH1A1 (0.32) ALDH1A1
Hydrochloric Acid SCHEMBL1073648 0.62 ALDH1A1 (0.32) ALDH1A1
SCHEMBL28005815 0.62 MEN1 (0.35) MITFALDH1A1MAPTHTTNPSR1
SCHEMBL23433023 0.62 PDE4B (0.33) PDE4BMITFALDH1A1MAPTHTT
SCHEMBL11753216 0.61 ALDH1A1 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5922763-A ANTICOAGULANT; CARDIOVASCULAR DISORDERS DR. KARL THOMAE GMBH (DE) 1999-07-13 US disclosed