Hydrochloric Acid

Hydrochloric Acid

SCHEMBL1073648

C1=CC(c2ccccc2)=C([Zr+2]C2=C(c3ccccc3)C=CC2)C1.[Cl-].[Cl-]

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride Ion SCHEMBL1130346 0.96 ALDH1A1 (0.32) ALDH1A1
Hydrochloric Acid SCHEMBL3682862 0.83
Hydrochloric Acid SCHEMBL7171600 0.83 POLB (0.33)
Hydrochloric Acid SCHEMBL7566921 0.80 CYP1A2 (0.32) ALDH1A1
Hydrochloric Acid SCHEMBL7572280 0.76 KIF11 (0.40) ALDH1A1NOTUM
Hydrochloric Acid SCHEMBL9066347 0.76 DYRK1A (0.46) NOTUM
Hydrochloric Acid SCHEMBL16424309 0.75 CHRNB2 (0.31)
Hydrochloric Acid SCHEMBL7566924 0.73 NISCH (0.35) ALDH1A1NOTUM
Hydrochloric Acid SCHEMBL7932885 0.72 CHRNB4 (0.34) NOTUM
Hydrochloric Acid SCHEMBL7935380 0.72 NISCH (0.34) NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1123299-A1 PREPARATION OF BIS ARYL CYCLOPENTADIENYL GROUP IVA METAL DIHALIDES BOULDER SCIENTIFIC COMPANY (US) 2001-08-16 EP claimed
WO-2001014389-A1 PREPARATION OF BIS ARYL CYCLOPENTADIENYL GROUP IVA METAL DIHALIDES BOULDER SCIENTIFIC COMPANY (US) 2001-03-01 WO claimed
US-6124489-A Preparation of bis aryl cyclopentadienyl Group IVA metal dihalides BOULDER SCIENTIFIC COMPANY (US) 2000-09-26 US claimed
EP-0540108-B1 Catalyst composition SHELL INT RESEARCH (NL) 1996-01-03 EP claimed
US-5279999-A Catalyst composition SHELL OIL COMPANY (US) 1994-01-18 US claimed
EP-0540108-A1 Catalyst composition SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-05-05 EP claimed
EP-3074450-B1 MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES MOMENTIVE PERFORMANCE MAT INC (US) 2020-11-11 EP disclosed
CN-105793326-B Moisture-curable compositions with metal-arene complexes 莫门蒂夫性能材料股份有限公司 2020-07-21 CN disclosed
US-10174169-B2 Moisture curable compound with metal-arene complexes MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-01-08 US disclosed
US-20170260335-A1 MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES MOMENTIVE PERFORMANCE MATERIALS INC. 2017-09-14 US disclosed
EP-2576642-B1 PROCESS FOR PREPARING A SUPPORTED CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, THE CATALYST SYSTEM AND ITS USE BASELL POLYOLEFINE GMBH (DE) 2017-08-16 EP disclosed
EP-1824888-B1 MONOCYCLOPENTADIENYL COMPLEXES BASELL POLYOLEFINE GMBH (DE) 2017-01-18 EP disclosed
EP-3074450-A1 MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES Momentive Performance Materials Inc. (US) 2016-10-05 EP disclosed
WO-2002000436-A2 METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENE AND LOW DENSITY POLYETHYLENE BLENDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-01-03 WO disclosed
WO-2001098409-A1 VERY LOW DENSITY POLYETHYLENE AND HIGH DENSITY POLYETHYLENE BLENDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2001-12-27 WO disclosed
WO-2001098372-A2 METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENES EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2001-12-27 WO disclosed
WO-2001098406-A2 POLYETHYLENE BLENDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2001-12-27 WO disclosed
US-6262196-B1 AS POLYMERIZATION CATALYST IN POLYMERIZATION OF OLEFINS TARGOR GMBH (DE) 2001-07-17 US disclosed
US-5279999-A Catalyst composition SHELL OIL COMPANY (US) 1994-01-18 US disclosed
EP-0576213-A2 Process for polymerizing olefins MITSUBISHI CHEMICAL CORPORATION (JP) 1993-12-29 EP disclosed