Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409078 | 0.85 | GPR119 (0.46) | KDM4EPKMGPR119POLB | |
| SCHEMBL8409489 | 0.84 | GPR119 (0.47) | KDM4EPKMGPR119POLB | |
| SCHEMBL8409517 | 0.82 | GPR119 (0.45) | KDM4EPKMGPR119POLB | |
| SCHEMBL8793652 | 0.82 | GPR119 (0.45) | GPR119POLB | |
| SCHEMBL8406581 | 0.81 | GPR119 (0.52) | GPR119POLB | |
| SCHEMBL3336117 | 0.78 | GPR119 (0.54) | GPR119POLB | |
| SCHEMBL8409617 | 0.77 | GPR119 (0.50) | GPR119POLB | |
| SCHEMBL3035919 | 0.75 | GRIN2B (0.68) | KDM4EPKMGPR119TGFBR1GRIN2B | |
| SCHEMBL1307415 | 0.75 | GPR119 (0.60) | GPR119 | |
| SCHEMBL24380660 | 0.75 | KDM4E (0.54) | KDM4EPKMGPR119GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866589-A | Alkyl substituted piperadinyl and piperazinyl anti-AIDS compounds | PHARMACIA & UPJOHN COMPANY (US) | 1999-02-02 | — | — | US | disclosed |
| WO-1996018628-A1 | ALKYL SUBSTITUTED PIPERADINYL AND PIPERAZINYL ANTI-AIDS COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 1996-06-20 | — | — | WO | disclosed |