Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | CPA1 | P15085 | 1/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16480336 | 0.91 | TSHR (0.44) | TSHRTRPA1ALDH1A1TDP1MME | |
| SCHEMBL106965 | 0.91 | TSHR (0.44) | TSHRTRPA1ALDH1A1TDP1MME | |
| SCHEMBL16480337 | 0.91 | TSHR (0.44) | TSHRTRPA1ALDH1A1TDP1MME | |
| SCHEMBL16280836 | 0.91 | TSHR (0.44) | TSHRTRPA1ALDH1A1TDP1MME | |
| SCHEMBL108664 | 0.87 | TSHR (0.53) | TSHRTRPA1LMNAALDH1A1TDP1 | |
| SCHEMBL12409518 | 0.84 | TSHR (0.47) | TSHRTRPA1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL15496474 | 0.84 | TSHR (0.47) | TSHRTRPA1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL414431 | 0.84 | TSHR (0.47) | TSHRTRPA1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL15889665 | 0.83 | LMNA (0.43) | TSHRTRPA1LMNAL3MBTL1TDP1 | |
| SCHEMBL13893015 | 0.83 | LMNA (0.43) | TSHRTRPA1LMNAL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129505-B2 | Formed by catalytic polymerization; antibody conjugates | UCB PHARMA S.A. (BE) | 2012-03-06 | — | — | US | disclosed |