Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15496474 | 1.00 | TSHR (0.47) | TSHRLMNAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL12409518 | 1.00 | TSHR (0.47) | TSHRLMNAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL16280839 | 0.92 | TSHR (0.47) | TSHRLMNAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL632560 | 0.92 | TSHR (0.47) | TSHRLMNAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL15704275 | 0.92 | TSHR (0.47) | TSHRLMNAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL11974290 | 0.87 | TSHR (0.44) | TSHRLMNAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL17528489 | 0.87 | LMNA (0.69) | TSHRLMNAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL13893119 | 0.87 | TSHR (0.44) | TSHRLMNAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL13296278 | 0.87 | TSHR (0.44) | TSHRLMNAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL15895192 | 0.87 | LMNA (0.69) | TSHRLMNAL3MBTL1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160235736-A1 | ANTIMICROBIAL COMPOSITIONS | MELINTA SUBSIDIARY CORP. | 2016-08-18 | — | — | US | disclosed |
| US-20150366857-A1 | Antimicrobial Compositions with Effervescent Agents | MELINTA SUBSIDIARY CORP. | 2015-12-24 | — | — | US | disclosed |
| US-20150366858-A1 | Methods for Treating Infections | MELINTA SUBSIDIARY CORP. (F/K/A MELINTA THERAPEUTICS, INC.) | 2015-12-24 | — | — | US | disclosed |
| US-20120065186-A1 | ANTIMICROBIAL COMPOSITIONS | RIB-X PHARMACEUTICALS, INC. | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160235736-A1 | ANTIMICROBIAL COMPOSITIONS | NOD2, QPCT, IFNG | TSHR 4804/4885LMNA 2946/4885L3MBTL1 3140/4885 |
| US-20150366858-A1 | Methods for Treating Infections | LPO, FABP2, IL5 | TSHR 4058/4885LMNA 4060/4885L3MBTL1 1869/4885 |
| US-20150366857-A1 | Antimicrobial Compositions with Effervescent Agents | OPA1, FPR1, NOD2 | TSHR 4814/4885LMNA 3017/4885L3MBTL1 4433/4885 |
| US-20120065186-A1 | ANTIMICROBIAL COMPOSITIONS | NOD2, QPCT, IFNG | TSHR 4804/4885LMNA 2946/4885L3MBTL1 3140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.