Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 5/20 | 0.31 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562427 | 0.85 | AR (0.32) | PGR | |
| SCHEMBL8618594 | 0.84 | PGR (0.38) | PGRCYP1B1 | |
| SCHEMBL8407055 | 0.82 | PGR (0.42) | PGRCYP17A1CYP21A2 | |
| SCHEMBL8407082 | 0.82 | PGR (0.42) | PGRCYP17A1CYP21A2 | |
| SCHEMBL8538113 | 0.79 | PGR (0.47) | PGR | |
| SCHEMBL8407038 | 0.75 | PGR (0.36) | PGRCYP17A1 | |
| SCHEMBL8409808 | 0.75 | PGR (0.36) | PGRCYP17A1 | |
| SCHEMBL8536623 | 0.72 | PGR (0.39) | PGRCYP17A1CYP21A2 | |
| SCHEMBL8409402 | 0.71 | CYP1B1 (0.42) | PGRCYP1B1CYP17A1CYP21A2 | |
| SCHEMBL8539945 | 0.71 | PGR (0.48) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565553-B1 | 6,7-MODIFIED 11$g(b)-ARYL-4-ESTRENES | SCHERING AG (DE) | 1999-07-21 | — | — | EP | disclosed |
| US-5843931-A | 6,7-modified 11β-aryl-4-oestrenes | SHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |