Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 17/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 13/20 | 0.38 |
| ▸ | AR | P10275 | 10/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623060 | 0.85 | CYP17A1 (0.32) | PGRNR3C1AR | |
| SCHEMBL8621140 | 0.85 | NR3C1 (0.41) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL8409732 | 0.84 | PGR (0.35) | PGRCYP1B1 | |
| SCHEMBL8409400 | 0.82 | PGR (0.44) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8409402 | 0.71 | CYP1B1 (0.42) | PGRARCYP1B1 | |
| SCHEMBL9019827 | 0.71 | NR3C1 (0.59) | PGRNR3C1ARCYP3A4CYP2C8 | |
| SCHEMBL8562427 | 0.68 | AR (0.32) | PGRNR3C1AR | |
| SCHEMBL8427264 | 0.67 | PGR (0.49) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8407055 | 0.67 | PGR (0.42) | PGRNR3C1ARCYP3A4 | |
| SCHEMBL8407082 | 0.67 | PGR (0.42) | PGRNR3C1ARCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843931-A | 6,7-modified 11β-aryl-4-oestrenes | SHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |