Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16892550 | 0.86 | MEN1 (0.61) | TAAR1ATMSIGMAR1TMEM97L3MBTL1 | |
| SCHEMBL5917175 | 0.85 | L3MBTL1 (0.64) | TAAR1ATMSIGMAR1TMEM97L3MBTL1 | |
| SCHEMBL10156581 | 0.82 | TAAR1 (0.76) | TAAR1ATMSIGMAR1TMEM97MAPT | |
| SCHEMBL17919923 | 0.78 | TAAR1 (0.64) | TAAR1ATMSIGMAR1TMEM97MAPT | |
| SCHEMBL28291658 | 0.77 | SIGMAR1 (0.41) | TAAR1ATMSIGMAR1MAPTLMNA | |
| SCHEMBL1243518 | 0.77 | — | — | |
| SCHEMBL6576818 | 0.76 | GFER (0.40) | TAAR1ALOX15HSD17B10ALDH1A1HPGD | |
| SCHEMBL1878 | 0.75 | TAAR1 (1.00) | TAAR1ATMSIGMAR1TMEM97MAPT | |
| SCHEMBL19355275 | 0.75 | TAAR1 (1.00) | TAAR1ATMSIGMAR1TMEM97MAPT | |
| SCHEMBL27825237 | 0.74 | TAAR1 (0.57) | TAAR1ATMSIGMAR1TMEM97MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1250548-C | Novel adenine derivatives | SUMITOMO PHARMA (JP) | 2006-04-12 | — | — | CN | disclosed |
| CN-1512992-A | Novel adenine derivatives | ס����ҩ��ʽ���� | 2004-07-14 | — | — | CN | disclosed |
| US-5955465-A | USEFUL IN THE DIAGNOSIS AND TREATMENT OF ANXIETY, SLEEP, AND SEIZURE DISORDERS, OVERDOSE WITH BENZODIAZEPINE DRUGS, AND ENHANCEMENT OF MEMORY | NEUROGEN CORPORATION (US) | 1999-09-21 | — | — | US | disclosed |
| EP-0221344-B1 | SULPHONYL-PHENYL ALKYL AMINES, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1990-05-23 | — | — | EP | disclosed |
| EP-0221344-A1 | Sulphonyl-phenyl alkyl amines, process for their preparation and medicines | Roche Diagnostics GmbH (DE) | 1987-05-13 | — | — | EP | disclosed |