Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.71 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.71 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP10 | P09238 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
| ▸ | CFD | P00746 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885483 | 0.90 | SELP (0.57) | ITGB3ITGA2BKMT2AMEN1MMP2 | |
| SCHEMBL8410944 | 0.87 | ITGB3 (0.93) | ITGB3ITGA2BFFAR1PPARDNR1H4 | |
| Hydrochloric Acid SCHEMBL8720248 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BITGB1ITGA4KMT2A | |
| SCHEMBL7864280 | 0.83 | ITGB3 (0.62) | ITGB3ITGA2BITGB1ITGA4FFAR1 | |
| Hydrochloric Acid SCHEMBL8410685 | 0.81 | KMT2A (0.52) | ITGB3ITGA2BKMT2AMEN1CFD | |
| SCHEMBL9335733 | 0.79 | ITGB3 (0.56) | ITGB3ITGA2BKMT2AMEN1GAA | |
| SCHEMBL7457414 | 0.78 | ITGB3 (0.84) | ITGB3ITGA2BITGB1PPARDNR1H4 | |
| SCHEMBL8408026 | 0.78 | ITGB3 (0.72) | ITGB3ITGA2BPPARDNR1H4 | |
| SCHEMBL9293507 | 0.78 | ITGB3 (0.67) | ITGB3ITGA2BKMT2AMEN1MAPT | |
| SCHEMBL7383956 | 0.76 | ITGB3 (0.65) | ITGB3ITGA2BITGB1ITGA4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922763-A | ANTICOAGULANT; CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |
| EP-0496378-B1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | THOMAE GMBH DR K (DE) | 1995-09-20 | — | — | EP | disclosed |
| EP-0496378-A1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |