Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410329 | 1.00 | L3MBTL1 (0.50) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL18561876 | 1.00 | L3MBTL1 (0.50) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL9649819 | 0.89 | L3MBTL1 (0.42) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL3116497 | 0.88 | CYP1A2 (0.53) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL27932302 | 0.86 | CYP1A2 (0.52) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL10406964 | 0.85 | L3MBTL1 (0.49) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL19615380 | 0.85 | L3MBTL1 (0.49) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL4036129 | 0.85 | L3MBTL1 (0.49) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL27622392 | 0.85 | L3MBTL1 (0.49) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL24346289 | 0.84 | CYP1A2 (0.50) | KMT2APOLBCYP1A2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718645-B2 | Macrocyclic therapeutic agents, methods of manufacture, and methods of treatment | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-08-08 | — | — | US | disclosed |
| US-20170057996-A1 | MACROCYCLIC THERAPEUTIC AGENTS, METHODS OF MANUFACTURE, AND METHODS OF TREATMENT | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2017-03-02 | — | — | US | disclosed |
| EP-0690049-B1 | Agent for treating hepato biliary diseases | R TECH UENO LTD (JP) | 1999-08-04 | — | — | EP | disclosed |
| US-5739161-A | PROSTAGLANDINS; DIARRHEA SIDE EFFECT REDUCTION | R-TECH UENO, LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0690049-A2 | Agent for treating hepato biliary diseases | R-TECH UENO LTD. (JP) | 1996-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718645-B2 | Macrocyclic therapeutic agents, methods of manufacture, and methods of treatment | NFATC1, MCL1, ICOS | L3MBTL1 3925/4885KMT2A 2181/4885POLB 2077/4885 |
| US-20170057996-A1 | MACROCYCLIC THERAPEUTIC AGENTS, METHODS OF MANUFACTURE, AND METHODS OF TREATMENT | NFATC1, MCL1, ICOS | L3MBTL1 3925/4885KMT2A 2181/4885POLB 2077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.