Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434247 | 0.88 | KMT2A (0.47) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL9779602 | 0.86 | ACE2 (0.50) | L3MBTL1KMT2APOLBCYP1A2ALDH1A1 | |
| SCHEMBL18803112 | 0.86 | DGKA (0.44) | L3MBTL1POLBALDH1A1TSHRMAPT | |
| SCHEMBL11652884 | 0.86 | GABRP (0.48) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL8410329 | 0.85 | L3MBTL1 (0.50) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL18561876 | 0.85 | L3MBTL1 (0.50) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL8410331 | 0.85 | L3MBTL1 (0.50) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL29134114 | 0.85 | ACE2 (0.53) | L3MBTL1KMT2APOLBCYP1A2ALDH1A1 | |
| SCHEMBL2245530 | 0.84 | CYP1A2 (0.52) | L3MBTL1KMT2APOLBCYP1A2GAA | |
| SCHEMBL6067665 | 0.83 | L3MBTL1 (0.49) | L3MBTL1KMT2APOLBCYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096734-A1 | MICROCAPSULES | FMC CORPORATION (US) | 2025-05-08 | — | — | WO | disclosed |
| CN-109810589-A | Light converts resin combination, light conversion layer folds substrate and image display device | 东友精细化工有限公司 | 2019-05-28 | — | — | CN | disclosed |
| US-9981903-B2 | Method for preparing di- or tricarboxylic esters by alkoxycarbonylation of dienes having conjugated double bonds | EVONIK DEGUSSA GMBH (DE) | 2018-05-29 | — | — | US | disclosed |
| CN-105622416-B | The preparation method for the compound that a kind of fluorene group and carboxylate combine | 中国石油化工股份有限公司 | 2018-05-11 | — | — | CN | disclosed |
| US-20180022687-A1 | METHOD FOR PREPARING DI- OR TRICARBOXYLIC ESTERS BY ALKOXYCARBONYLATION OF DIENES HAVING CONJUGATED DOUBLE BONDS | EVONIK DEGUSSA GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| EP-1444211-B1 | QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS | ASTRAZENECA AB (SE) | 2009-01-21 | — | — | EP | disclosed |
| US-20070088044-A1 | Quinazoline derivatives as antitumor agents | ASTRAZENECA AB | 2007-04-19 | — | — | US | disclosed |
| CN-1764651-A | Quinazoline derivatives as antitumor agents | ASTRAZENECA AB (SE) | 2006-04-26 | — | — | CN | disclosed |
| US-6953809-B2 | Monocyte chemoattractant protein-1 inhibitor compounds | ZENECA LIMITED (GB) | 2005-10-11 | — | — | US | disclosed |
| US-20050054662-A1 | Quinazoline derivatives as antitumor agents | ASTRAZENECA AB (SE) | 2005-03-10 | — | — | US | disclosed |
| CN-1291094-A | Bicyclic pyrrole derivatives as MCP-1 inhibitor | ASTRA ZENECA BRITISH CO LTD (GB) | 2001-04-11 | — | — | CN | disclosed |
| EP-1056451-A1 | BICYCLIC PYRROLE DERIVATIVES AS MCP-1 INHIBITORS | AstraZeneca UK Limited (GB) | 2000-12-06 | — | — | EP | disclosed |
| EP-1054667-A1 | BICYCLIC PYRROLE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE AS ANTIINFLAMMATORY AND IMMUNOMODULATING AGENTS | AstraZeneca UK Limited (GB) | 2000-11-29 | — | — | EP | disclosed |
| CN-1265591-A | Coumpound | ZENECA LTD (GB) | 2000-09-06 | — | — | CN | disclosed |
| EP-1003504-A2 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 ANTAGONISTS | AstraZeneca UK Limited (GB) | 2000-05-31 | — | — | EP | disclosed |
| EP-1001935-A1 | INDOLE DERIVATIVES AS MCP-1 RECEPTOR ANTAGONISTS | ZENECA LIMITED (GB) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999040914-A1 | BICYCLIC PYRROLE DERIVATIVES AS MCP-1 INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-08-19 | — | — | WO | disclosed |
| WO-1999040913-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA UK LIMITED (GB) | 1999-08-19 | — | — | WO | disclosed |
| WO-1999007678-A1 | INDOLE DERIVATIVES AS MCP-1 RECEPTOR ANTAGONISTS | ZENECA LIMITED (GB) | 1999-02-18 | — | — | WO | disclosed |
| WO-1999007351-A2 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 ANTAGONISTS | ZENECA LIMITED (GB) | 1999-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022687-A1 | METHOD FOR PREPARING DI- OR TRICARBOXYLIC ESTERS BY ALKOXYCARBONYLATION OF DIENES HAVING CONJUGATED DOUBLE BONDS | C9, PC, CBR3 | L3MBTL1 760/4885KMT2A 2960/4885POLB 1033/4885 |
| US-20050054662-A1 | Quinazoline derivatives as antitumor agents | ERBB2, ERBB3, ABL1 | L3MBTL1 3696/4885KMT2A 1693/4885POLB 2618/4885 |
| US-20070088044-A1 | Quinazoline derivatives as antitumor agents | ERBB2, EGFR, ERBB4 | L3MBTL1 4594/4885KMT2A 1786/4885POLB 2324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.