Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | UBE2N | P61088 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468814 | 0.91 | NPSR1 (0.48) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12588865 | 0.89 | NPSR1 (0.46) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12646434 | 0.88 | MAPK1 (0.50) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8930354 | 0.88 | MAPK1 (0.50) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8086906 | 0.88 | MAPK1 (0.55) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8616165 | 0.87 | MAPK1 (0.49) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6313496 | 0.87 | MAPK1 (0.49) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8410429 | 0.87 | MAPK1 (0.49) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8468433 | 0.86 | NPSR1 (0.40) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8083617 | 0.84 | MAPK1 (0.48) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869735-A | Process for the preparation of alkyl aryl ethers containing carboxyl groups | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-09 | — | — | US | disclosed |