Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408085 | 0.95 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4EHTTMAPK1 | |
| SCHEMBL8410852 | 0.91 | ALDH1A1 (0.73) | ALDH1A1MAPTKDM4EHTTMAPK1 | |
| SCHEMBL8407894 | 0.86 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EHTTMAPK1 | |
| SCHEMBL7941155 | 0.84 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EHTTMAPK1 | |
| SCHEMBL8407759 | 0.81 | ALDH1A1 (0.79) | ALDH1A1MAPTKDM4EHTTMAPK1 | |
| SCHEMBL7943222 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4EHTTMAPK1 | |
| SCHEMBL2913386 | 0.79 | ALOX15 (0.50) | ALDH1A1MAPTKDM4EHTTMAPK1 | |
| SCHEMBL7943159 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EHTTMAPK1 | |
| SCHEMBL8409980 | 0.78 | ALDH1A1 (0.68) | ALDH1A1MAPTKDM4EHTTMAPK1 | |
| SCHEMBL6416102 | 0.78 | ALOX15 (0.50) | ALDH1A1MAPTKDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874494-A | DETERIORATION STABILIZER FOR THERMOPLASTIC RESIN; OXIDATION RESISTANCE, DISCOLORATION INHIBITION, HEAT RESISTANCE, CROSSLINKING INHIBITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |