Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.53 |
| ▸ | CTSL | P07711 | 13/20 | 0.53 |
| ▸ | CTSS | P25774 | 12/20 | 0.53 |
| ▸ | CTSB | P07858 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7025275 | 1.00 | CTSK (0.53) | CTSKCTSLCTSSCTSBMEN1 | |
| SCHEMBL5934732 | 0.84 | CTSK (0.63) | CTSKCTSLCTSSCTSBMEN1 | |
| SCHEMBL7469816 | 0.81 | CTSK (0.47) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7444979 | 0.81 | CTSK (0.47) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5934816 | 0.80 | CTSK (0.49) | CTSKCTSLCTSSCTSBMEN1 | |
| SCHEMBL5934989 | 0.79 | CTSK (0.65) | CTSKCTSLCTSSCTSB | |
| SCHEMBL8410653 | 0.79 | CTSK (0.65) | CTSKCTSLCTSSCTSB | |
| SCHEMBL5934815 | 0.79 | CTSK (0.65) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7159854 | 0.77 | CTSK (0.60) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7473436 | 0.77 | CTSK (0.60) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929571-A1 | 4-SUBSTITUTED-3-(2-AMINO-2-CYCLOALKYL METHYL)-ACETAMIDO AZETIDIN-2-ONE DERIVATIVES AS CYSTEINE PROTEINASE REGULATORS | SYNPHAR LABORATORIES INC. (CA) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998012210-A1 | 4-SUBSTITUTED-3-(2-AMINO-2-CYCLOALKYL METHYL)-ACETAMIDO AZETIDIN-2-ONE DERIVATIVES AS CYSTEINE PROTEINASE REGULATORS | SYNPHAR LABORATORIES INC. (US) | 1998-03-26 | — | — | WO | disclosed |