Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.60 |
| ▸ | CTSL | P07711 | 14/20 | 0.60 |
| ▸ | CTSS | P25774 | 13/20 | 0.60 |
| ▸ | CTSB | P07858 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7159854 | 0.86 | CTSK (0.60) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7448401 | 0.84 | CTSK (0.46) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7494546 | 0.84 | CTSK (0.72) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7475989 | 0.82 | CTSK (0.54) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7473433 | 0.78 | CTSL (0.79) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7469816 | 0.77 | CTSK (0.47) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7444979 | 0.77 | CTSK (0.47) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7025275 | 0.77 | CTSK (0.53) | CTSKCTSLCTSSCTSB | |
| SCHEMBL8410658 | 0.77 | CTSK (0.53) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7445956 | 0.76 | CTSK (0.76) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950046-B1 | 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS | NAEJA PHARMACEUTICAL INC (CA) | 2002-04-10 | — | — | EP | claimed |