Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410668 | 1.00 | NPSR1 (0.50) | NPSR1CES2PNMTADAMTS4MMP13 | |
| SCHEMBL8463038 | 1.00 | NPSR1 (0.50) | NPSR1CES2PNMTADAMTS4MMP13 | |
| SCHEMBL8461896 | 0.84 | RXFP1 (0.46) | NPSR1CES2PNMTADAMTS4MMP13 | |
| SCHEMBL8459838 | 0.82 | CES2 (0.42) | CES2ALDH1A1 | |
| SCHEMBL8460849 | 0.82 | CES2 (0.42) | CES2ALDH1A1 | |
| SCHEMBL3077103 | 0.81 | CES2 (0.50) | NPSR1CES2PNMTADAMTS4MMP13 | |
| SCHEMBL514285 | 0.79 | EPHX1 (0.49) | NPSR1CES2PNMTADAMTS4MMP13 | |
| SCHEMBL30415685 | 0.78 | SMN1; SMN2 (0.55) | NPSR1CES2PNMTMEN1KMT2A | |
| SCHEMBL30416026 | 0.78 | SMN1; SMN2 (0.55) | NPSR1CES2PNMTMEN1KMT2A | |
| SCHEMBL8460231 | 0.78 | OGG1 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11049737-A | — | — | None | — | — | JP | disclosed |
| EP-0949243-A1 | OPTICALLY ACTIVE METHOXYIMINOACETAMIDE DERIVATIVES, PROCESS FOR THE PREPARATION OF THEM, INTERMEDIATES THEREFOR, AND PESTICIDES CONTAINING THEM AS THE ACTIVE INGREDIENT | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-10-13 | — | — | EP | disclosed |
| JP-H1149737-A | OPTICALLY ACTIVE 1-ARYLETHOXYAMINE DERIVATIVE AND ITS PRODUCTION | MITSUBISHI CHEM CORP | 1999-02-23 | — | — | JP | disclosed |