Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.48 |
| ▸ | PTGIR | P43119 | 18/20 | 0.48 |
| ▸ | PTGDR | Q13258 | 7/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410744 | 0.80 | TBXAS1 (0.58) | TBXAS1PTGIRPTGDR | |
| SCHEMBL8412819 | 0.79 | PTGIR (0.47) | TBXAS1PTGIRPTGDR | |
| SCHEMBL8413479 | 0.78 | TBXAS1 (0.37) | TBXAS1PTGIR | |
| SCHEMBL8413362 | 0.78 | PTGIR (0.62) | PTGIRPTGDR | |
| SCHEMBL8413612 | 0.75 | PTGIR (0.59) | TBXAS1PTGIRPTGDR | |
| SCHEMBL8412795 | 0.74 | TBXAS1 (0.44) | TBXAS1PTGIRPTGDR | |
| SCHEMBL8580253 | 0.74 | ADORA2A (0.32) | — | |
| SCHEMBL8412758 | 0.72 | PTGIR (0.63) | TBXAS1PTGIRPTGDR | |
| SCHEMBL8808707 | 0.72 | PTGIR (0.46) | TBXAS1PTGIRPTGDR | |
| SCHEMBL8410748 | 0.69 | TBXAS1 (0.49) | TBXAS1PTGIRPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | claimed |
| EP-0548949-B1 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1997-09-17 | — | — | EP | claimed |
| EP-0548949-A2 | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-30 | — | — | EP | claimed |
| US-5962439-A | CARDIOVASCULAR DISORDER | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5849919-A | Fused benzeneoxyacetic acid derivatives which have PGI2 receptor anonist activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |