Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP9 | P55211 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.45 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.45 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | MAP3K9 | P80192 | 3/20 | 0.41 |
| ▸ | MAP3K11 | Q16584 | 3/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27664385 | 0.77 | GSK3B (0.50) | TDP2CASP3CASP7CASP9CASP6 | |
| SCHEMBL121405 | 0.77 | GSK3B (0.50) | TDP2CASP3CASP7CASP9CASP6 | |
| SCHEMBL8410815 | 0.76 | TDP2 (0.47) | TDP2CASP3CASP7CASP9CASP6 | |
| SCHEMBL11120799 | 0.75 | GSK3B (0.48) | TDP2CASP3CASP7CASP9CASP6 | |
| SCHEMBL524602 | 0.75 | PNMT (0.63) | TDP2CASP3CASP7CASP9CASP6 | |
| SCHEMBL30103334 | 0.75 | PNMT (0.63) | TDP2CASP3CASP7CASP9CASP6 | |
| SCHEMBL1050913 | 0.74 | GSK3B (0.41) | TDP2CASP3CASP7CASP9CASP6 | |
| SCHEMBL2877998 | 0.73 | PNMT (0.61) | TDP2CASP3CASP7CASP9CASP6 | |
| SCHEMBL17025667 | 0.72 | PARP1 (0.34) | TDP2GSK3BPARP1PARP10PARP11 | |
| SCHEMBL29011874 | 0.71 | GSK3B (0.40) | TDP2CASP3CASP7CASP9CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10332695-A | — | — | None | — | — | JP | disclosed |
| US-5965746-A | REACTING AN AMINO GROUP-CONTAINING N-CYCLIC COMPOUND WITH MALEIC ANHYDRIDE IN ACETIC ACID TO OBTAIN AN N-CYCLIC MALEAMIC ACID, ADDING HEXAMETHYLDISILAZANE, CYCLIZING TO FORM N-CYCLIC MALEIMIDE, USE AS A FLUORESCENT DYES | AISIN SEIKI KABUSHIKI KAISHA (JP) | 1999-10-12 | — | — | US | disclosed |
| JP-H10332695-A | DETECTION OF NUCLEIC ACID, PROTEIN, OR THE LIKE | AISIN SEIKI CO LTD | 1998-12-18 | — | — | JP | disclosed |