SCHEMBL8410833

SCHEMBL8410833

CC(C)OS(=O)(=O)c1ccccc1C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
HSD11B1 P28845 2/20 0.44
SLC22A12 Q96S37 13/20 0.43
ALDH1A1 P00352 1/20 0.39
CYP2C9 P11712 1/20 0.38
SLC22A6 Q4U2R8 1/20 0.38
SLC22A8 Q8TCC7 1/20 0.38
SLC22A11 Q9NSA0 1/20 0.38
MMP7 P09237 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL940476 0.82 MMP7 (0.47) KMT2AMEN1SLC22A12ALDH1A1CYP2C9
SCHEMBL16044746 0.81 ALDH1A1 (0.40) KMT2AMEN1ALDH1A1CYP2C9
SCHEMBL29415231 0.81 ALDH1A1 (0.40) KMT2AMEN1ALDH1A1CYP2C9
SCHEMBL13290746 0.80 KMT2A (0.51) KMT2AMEN1HSD11B1SLC22A12ALDH1A1
SCHEMBL8409554 0.77 SLC22A12 (0.41) SLC22A12ALDH1A1
SCHEMBL10157175 0.77 KMT2A (0.51) KMT2AMEN1HSD11B1SLC22A12ALDH1A1
SCHEMBL28241695 0.77 MEN1 (0.51) KMT2AMEN1HSD11B1SLC22A12ALDH1A1
SCHEMBL8412725 0.77 KMT2A (0.42) KMT2AMEN1HSD11B1ALDH1A1
SCHEMBL27550502 0.77 MEN1 (0.51) KMT2AMEN1HSD11B1SLC22A12ALDH1A1
SCHEMBL28266652 0.77 MEN1 (0.51) KMT2AMEN1HSD11B1SLC22A12ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3276735-B1 NONAQUEOUS ELECTROLYTE FOR SODIUM SECONDARY BATTERY AND SODIUM SECONDARY BATTERY SUMITOMO CHEMICAL CO (JP) 2023-07-12 EP disclosed
CN-107431246-B Nonaqueous electrolyte for sodium secondary battery and sodium secondary battery 住友化学株式会社 2021-03-09 CN disclosed
EP-3276735-A1 NONAQUEOUS ELECTROLYTE FOR SODIUM SECONDARY CELL, AND SODIUM SECONDARY CELL Sumitomo Chemical Company, Ltd. (JP) 2018-01-31 EP disclosed
CN-107431246-A Sodium rechargeable battery nonaqueous electrolytic solution and sodium rechargeable battery 住友化学株式会社 2017-12-01 CN disclosed
CN-1339432-A Extracting method for substituted phenyl compounds ROHM & HAAS (US) 2002-03-13 CN disclosed
CN-1070175-C Process for the preparation of 2, 6-disubstituted benzenesulfonates or 2, 6-disubstituted benzenesulfonates further substituted in the 3-, 4-or 5-position ROHM & HAAS (US) 2001-08-29 CN disclosed
EP-0708087-B1 Method for making a substituted benzene compound ROHM & HAAS (US) 1999-07-28 EP disclosed
CN-1174189-A Process for preparing substituted benzene compounds ROHM & HAAS (US) 1998-02-25 CN disclosed
US-5670691-A REACTION OF 2-SUBSTITUTED BENZENESULFONATE WITH LITHIUM COMPOUND THEN REACTION WITH ELECTROPHILE TO FORM 2,6-DISUBSTITUTED BENZENESULFONATE ROHM AND HAAS COMPANY (US) 1997-09-23 US disclosed
EP-0708087-A1 Method for making a substituted benzene compound ROHM AND HAAS COMPANY (US) 1996-04-24 EP disclosed