Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12674518 | 0.83 | ADRA2A (0.50) | ADRA2A | |
| SCHEMBL4743515 | 0.83 | ADRA2A (0.50) | ADRA2A | |
| Hydrochloric Acid SCHEMBL13269175 | 0.81 | ADRA2A (0.49) | ADRA2A | |
| Bromide SCHEMBL10357248 | 0.81 | ADRA2A (0.49) | ADRA2A | |
| SCHEMBL11668993 | 0.80 | ADRB2 (0.51) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL23114067 | 0.79 | CYP19A1 (0.39) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL23114068 | 0.79 | CYP19A1 (0.39) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL21091917 | 0.78 | ADRB2 (0.49) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL21091959 | 0.78 | ADRB2 (0.49) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL8902336 | 0.77 | ADRA2A (0.81) | ADRA2AADRA2BADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936125-A | Process for the preparation of 5,6-dihydroxy-2-amino-1,2,3,4-tetrahydronaphthalene derivatives | CHIESI FARMACEUTICI S.P.A. (IT) | 1999-08-10 | — | — | US | disclosed |