Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 4/20 | 0.46 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415074 | 1.00 | KMT2A (0.49) | KMT2AALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL8411691 | 0.87 | MAPT (0.52) | KMT2AALDH1A1MEN1MAPTTHRB | |
| SCHEMBL7567204 | 0.85 | NPC1 (0.47) | KMT2AALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL7571848 | 0.85 | AOX1 (0.52) | ALDH1A1POLBSMN1; SMN2RAB9AMAPT | |
| SCHEMBL8411863 | 0.85 | RAD52 (0.43) | KMT2AALDH1A1MEN1MAPTTHRB | |
| SCHEMBL7565816 | 0.84 | KMT2A (0.48) | KMT2AALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL7568267 | 0.84 | KMT2A (0.48) | KMT2AALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL8414320 | 0.83 | RAD52 (0.57) | KMT2AALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL7568269 | 0.78 | RAD52 (0.55) | KMT2AALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL7565820 | 0.78 | RAD52 (0.55) | KMT2AALDH1A1POLBSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |