Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 4/20 | 0.57 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566567 | 0.86 | RAD52 (0.47) | RAD52SMARCA2TAS1R3TAS1R1POLB | |
| SCHEMBL8411691 | 0.86 | MAPT (0.52) | RAD52SMARCA2TAS1R3TAS1R1MAPT | |
| SCHEMBL8411626 | 0.84 | RAD52 (0.65) | RAD52SMARCA2TAS1R3TAS1R1MAPT | |
| SCHEMBL8411181 | 0.84 | RAD52 (0.47) | RAD52SMARCA2TAS1R3TAS1R1MAPT | |
| SCHEMBL7568051 | 0.83 | TAS1R3 (0.51) | RAD52SMARCA2TAS1R3TAS1R1NQO2 | |
| SCHEMBL7573559 | 0.83 | RAD52 (0.48) | RAD52SMARCA2TAS1R3TAS1R1NQO2 | |
| SCHEMBL8415074 | 0.83 | KMT2A (0.49) | RAD52SMARCA2TAS1R3TAS1R1NQO2 | |
| SCHEMBL8411399 | 0.83 | KMT2A (0.49) | RAD52SMARCA2TAS1R3TAS1R1NQO2 | |
| SCHEMBL8224795 | 0.81 | RAD52 (0.85) | RAD52SMARCA2NQO2UHRF1ALDH1A1 | |
| SCHEMBL29634211 | 0.81 | RAD52 (0.85) | RAD52SMARCA2NQO2UHRF1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |