Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.54 |
| ▸ | HTR2A | P28223 | 4/20 | 0.54 |
| ▸ | HRH1 | P35367 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.54 |
| ▸ | HTR2C | P28335 | 3/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.54 |
| ▸ | HTR2B | P41595 | 3/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12933943 | 0.80 | CYP24A1 (0.37) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL2073576 | 0.80 | CYP24A1 (0.37) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL7774939 | 0.79 | POLB (0.41) | SLC6A4KDM4E | |
| SCHEMBL8126233 | 0.78 | LMNA (0.41) | SLC6A4CYP3A4KMT2ACYP2C19MEN1 | |
| SCHEMBL8623628 | 0.77 | CYP2C19 (0.41) | CYP2D6CYP1A2CYP3A4TSHRCYP2C19 | |
| SCHEMBL20528447 | 0.77 | CYP24A1 (0.38) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL8617087 | 0.77 | GSR (0.41) | SLC6A4CYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9499433 | 0.77 | SLC6A4 (0.71) | SLC6A4SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL3571695 | 0.76 | CYP24A1 (0.35) | SLC6A4CYP2D6CYP1A2CYP3A4LMNA | |
| SCHEMBL8580567 | 0.76 | CYP24A1 (0.35) | SLC6A4CYP3A4KMT2ACYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929514-A1 | PROCESS FOR THE PREPARATION OF FLUOXETINE | EGIS GYOGYSZERGYAR RT. (HU) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998011054-A1 | PROCESS FOR THE PREPARATION OF FLUOXETINE | EGIS Gyógyszergyár Rt. (HU) | 1998-03-19 | — | — | WO | disclosed |