Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CPA3 | P15088 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617087 | 0.81 | GSR (0.41) | CYP2C19ALDH1A1CYP1A2CYP2D6SLC6A9 | |
| SCHEMBL2073576 | 0.80 | CYP24A1 (0.37) | CYP2C19ALDH1A1CYP1A2CYP2D6TSHR | |
| SCHEMBL12933943 | 0.80 | CYP24A1 (0.37) | CYP2C19ALDH1A1CYP1A2CYP2D6TSHR | |
| SCHEMBL2729128 | 0.80 | TSHR (0.44) | CYP2C19ALDH1A1CYP1A2CYP2D6TSHR | |
| SCHEMBL7774939 | 0.79 | POLB (0.41) | ALDH1A1MMP13 | |
| SCHEMBL8126233 | 0.78 | LMNA (0.41) | CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL8411474 | 0.77 | SLC6A4 (0.59) | CYP2C19CYP1A2CYP2D6TSHRCYP3A4 | |
| SCHEMBL20528447 | 0.77 | CYP24A1 (0.38) | CYP2C19ALDH1A1CYP1A2CYP2D6TSHR | |
| SCHEMBL27623050 | 0.77 | KIF11 (0.38) | CYP2C19ALDH1A1CYP1A2CYP2D6TSHR | |
| SCHEMBL11643170 | 0.77 | PABPC1 (0.51) | CYP2C19ALDH1A1CYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657446-B1 | Process for producing optically active erythro-3-amino-1,2-epoxy compound | NIPPON KAYAKU KK (JP) | 1998-05-13 | — | — | EP | disclosed |
| US-5488118-A | Process for producing optically active erythro-3-amino-1,2-epoxy compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1996-01-30 | — | — | US | disclosed |
| EP-0657446-A1 | Process for producing optically active erythro-3-amino-1,2-epoxy compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1995-06-14 | — | — | EP | disclosed |